Daun mulberry (terutama Morus alba) kaya nutrien dan sebatian bioaktif; bukti manusia dan haiwan menunjukkan ia paling kukuh untuk gula darah dan risiko kardiometabolik, di samping kesan antioksidan dan anti‑radang.
Komposisi & cara tindakan
Daun mulberry mengandungi vitamin (A, B, C), serat, mineral (Ca, Fe, Mg, Zn), flavonoid, fenolik dan alkaloid khas seperti 1‑deoxynojirimycin (DNJ) dan fagomine (Sarkhel et al., 2020; Khakwani et al., 2022; et al., 2021). DNJ menghalang enzim pencernaan karbohidrat (α‑glukosidase, α‑amilase), melambatkan penyerapan gula dan merendahkan lonjakan glukosa selepas makan ( et al., 2021; Zhang et al., 2021; James et al., 2024). Antioksidan (flavonoid, polifenol) mengurangkan stres oksidatif dan keradangan, yang penting untuk jantung dan metabolisme ( et al., 2021; Thaipitakwong et al., 2018; Jan et al., 2021).
Khasiat kesihatan utama
| Khasiat | Ringkasan bukti | Sumber |
|---|---|---|
| Kawalan gula darah | Ekstrak/teh daun turunkan glukosa posprandial, tingkat sensitiviti insulin dalam kajian klinikal dan haiwan | (Zhang et al., 2021; Sarkhel et al., 2020; Thaipitakwong et al., 2018; James et al., 2024) |
| Anti‑kolesterol & anti‑lemak darah | Kurangkan trigliserida, LDL dan baiki profil lipid, menurunkan risiko kardiovaskular | ( et al., 2021; Li et al., 2024; Khawani et al., 2023; Thaipitakwong et al., 2018) |
| Anti‑obesiti & berat badan | Kurangkan pengumpulan lemak dan berat dalam model haiwan; sokongan klinikal awal | ( et al., 2021; Li et al., 2024; Thaipitakwong et al., 2018) |
| Tekanan darah & jantung | Kesan antihipertensi, anti‑aterosklerosis dan perlindungan vaskular | (Forsan et al., 2025; Qi et al., 2025; Thaipitakwong et al., 2018) |
| Antioksidan & anti‑radang umum | Kurangkan radikal bebas dan penanda keradangan; potensi lindungi hati, saraf, dan melambat penuaan sel | ( et al., 2021; Jan et al., 2021; Maqsood et al., 2022; Hao et al., 2022) |
Figure 1: Ringkasan khasiat klinikal utama daun mulberry.
Aplikasi & keselamatan
Daun mulberry digunakan sebagai teh herba, serbuk, kapsul dan ekstrak untuk sokongan metabolik (Zhang et al., 2021; Sarkhel et al., 2020; James et al., 2024). Secara umum dianggap selamat dalam dos makanan, tetapi standardisasi dos, tempoh penggunaan jangka panjang dan interaksi ubat (terutama ubat diabetes/tekanan darah) masih memerlukan kajian lanjut ( et al., 2021; Thaipitakwong et al., 2018; Maqsood et al., 2022).
Kesimpulan
Secara keseluruhan, daun mulberry ialah makanan fungsian yang menjanjikan untuk bantu kawal gula darah, lemak darah, tekanan darah dan perlindungan kardiometabolik, disokong oleh antioksidan dan anti‑radang; namun ia wajar dilihat sebagai pelengkap gaya hidup sihat dan bukan pengganti rawatan perubatan.
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References
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Forsan, H., Fayed, M., Farahat, N., Gabr, W., Alswerky, E., El-Hak, A., Fouda, M., & Safwat, M. (2025). Polyphenols of Mulberry White (Morus alba L.) Leaves as a Source of Functional Food: A Review. Al-Kitab Journal for Pure Sciences. https://doi.org/10.32441/kjps.09.02.p7
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